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Dr. Xiping Zhan

Xiping Zhan, Ph.D.

Research assistant professor

  • Physiology & Biophysics
  • College of Medicine


I am an Assistant Professor of Neuroscience at the Department of Physiology and Biophysics.  My scientific research has focused on elucidating the basic mechanisms in multisensory integration in auditory system, neurotoxicity and neurodegenerative diseases.  Specifically, we are working on striatal medium spiny and dopaminergic neurons, synaptic signaling and neuronal plasticity.  To accomplish our work, we use vitro neurophysiology and calcium imaging in mouse brain slices and iPSC derived neurons.  To test or confirm our work in vitro, we also employ in vivo neurophysiology combined with optogenetics and behavior measurements in anesthetized or awake animals.  My future research plan is fueled by my motivation of investigating the distinct, intricate and multilevel aspects of neurological diseases in mouse models and human patients.

Contact Information:

Office Location: Suite 413 Seeley G. Mudd Building

                          520 W Street, N.W.,  Washington, DC 20059

Laboratory Location: 409 - 413 Seeley G. Mudd Building 

                                  4108 Numa Adams Building

Laboratory Telephone: (202) 250 – 5236


Ph.D. East China Normal University (1999)

Postdoctoral Fellow:   Fudan University (1999 - 2001)

                                   Johns Hopkins University (2001 – 2008)

                                   Georgetown University (2008 - 2009)

Research interests

Ca homeostasis modulation, dysfunction in neurodegenerative diseases

Patient specific iPSCs, cellular neurophysiology and neurotoxicology

Multimodal sensory integration, negative sensation evaluation and tinnitus  


HUCM - BFPSAP (2014-2015)

Hearing Heath Foundation ERG Award (2015 - 2017)

Maryland Stem Cell Fund (2018-2019)

NINDS R21 (2020-2024)


Karen Toffler Charitable Trust (2022-23)

DC CFAR Pilot Award (2023-24)

Complete list of published work

My Bibliography - NCBI ( 

Jobs in the lab

Internship and research technician positions are available. Preferred candidates with a background in molecular biology, cell culture, histology or MATLAB are encouraged to apply.