Bioinformatics and Virology
Dr. Fayuan Wen is an Assistant Professor of Computational Biology within the Department of Biology. After receiving her PhD in Virology and Entomology from Chinese Academy of Forestry, she started her postdoctoral training in Cellular Biology and Bioinformatics at University of Guelph and Natural Resources of Canada. She then joined Howard University as a postdoc associate where she adeptly applies advanced computational biology techniques and biostatistical tools to biomedical and health research domains. Dr. Wen's expertise lies in the analysis of bioinformatics data from next-generation sequencing (NGS) such as RNA-seq and Whole Genome Sequencing (WGS). Her research trajectory encompasses diverse areas, including whole genome sequencing analysis of Sickle Cell Disease (SCD), investigations into gene regulation during host-virus interactions, cellular transcriptional responses to chemical treatments, and bioinformatics inquiries into overwintering insects.
Currently, Dr. Wen focuses on gene variant identification relevant to Iron Overload in Sickle Cell Disease, utilizing genome-wide association studies (GWAS) and machine learning-based Polygenic Risk Score Analysis. Additionally, her projects involve rigorous bioinformatics analysis of NGS data and biostatistical evaluations of electronic health record data, underscoring her multifaceted contributions to the field.