Doctor of Pharmacy (Pharm.D.)
Pharmacotherapy
University of Maryland
2017
Dhakrit “Jesse” Rungkitwattanakul, Pharm.D., BCPS, FNKF, FASN, is an associate professor in the Department of Clinical and Administrative Pharmacy Sciences at the Howard University College of Pharmacy. A board-certified pharmacotherapy specialist, he also maintains clinical practice at Howard University Hospital, where he works with the nephrology consult service and related clinical programs. Rungkitwattanakul earned his Doctor of Pharmacy from the University of Maryland School of Pharmacy and completed a postgraduate pharmacy practice residency at Georgetown University Hospital in Washington, D.C.
Rungkitwattanakul’s research centers on pharmacotherapy and medication management in patients with kidney disease. His work explores the prevention of drug-associated acute kidney disease and studies the integration of kidney stress biomarkers with clinical decision support systems to expand the pharmacist’s role in AKI/AKD prevention among high-risk patients through nephrotoxin stewardship programs. He has a particular interest in drug dosing and pharmacokinetics in critically ill patients with kidney impairment, including those receiving dialysis and continuous kidney replacement therapy, as well as medication safety and clinical outcomes across kidney disease populations. His research also addresses health equity and disparities in kidney disease care and medication use.
In addition to his research and teaching, Rungkitwattanakul is active in professional service and pharmacy education. He has contributed to curriculum development and residency training at Howard University and Howard University Hospital and has served in leadership roles in professional organizations related to clinical pharmacy and nephrology. His work has been recognized with multiple honors, including the Up and Coming Researcher of the Year Award from the Howard University Office of Research and professional recognition from regional and national pharmacy organizations.
Pharmacotherapy
University of Maryland
2017
Currently practicing at Howard University Hospital: Nephrology consult service and Nephrotoxin Stewardship service.
Principal investigator: The American Society of Health-System Pharmacists Foundation. Leveraging Clinical Decision Support System and Kidney Stress Biomarkers to Prevent Hospital-Acquired Acute Kidney Injury in High-Risk Populations. Description: the project examine the impact of clinical decision support systems (CDSS) and kidney stress biomarkers to identify at-risk patients who would “otherwise go undetected.” Award funded $50,000. Jun 2025-December 2026.
Training Coordinator: The Mid Atlantic AIDS Education and Training Center Howard University. Health Resources and Service Administration (HRSA). Local Partner Site (MAAETC HULPS). Award funded: 3% salary support; Award ID: 1 TR7HA53201-02-00, CDFA Number: 93.145. Description: Provide training in kidney disease management and prevention among adults living with HIV disease. Jul 2025-Jun 2026.
Limited evidence exists synthesizing the risk of acute kidney injury (AKI) associated with the concomitant administration of multiple nephrotoxic drugs, and even less examining the concept of nephrotoxic burden. The objective of this scoping review was to (1) identify definitions of nephrotoxic burden; (2) methods used to quantify (use of calculations) nephrotoxic burden; and (3) determine the association between nephrotoxic burden and AKI risk. Additionally, we assessed studies reporting the risk of AKI with the concurrent use of three or more nephrotoxic drugs.
Pharmacists play a critical role in optimizing medication use, especially in vulnerable populations such as those with chronic kidney disease (CKD). Despite strong evidence and recent guideline endorsements, many pharmacists continue to rely on the Cockcroft–Gault (C-G) equation for medication dosing. This opinion paper issues a call to action for the widespread adoption of a race-free, body surface area–adjusted estimated glomerular filtration rate (eGFRBSAadj) for medication-related decision-making, as endorsed by the 2024 Kidney Disease: Improving Global Outcomes CKD guidelines and the National Kidney Foundation and the American Society of Nephrology Taskforce.
The Monte Carlo simulation can be a useful tool to evaluate drug dosing in critically ill acute kidney injury patients receiving CRRT when limited pharmacokinetic data are a concern. Our simulation study reveals that the dosing regimen of piperacillin-tazobactam 12 g/day is appropriate for treating Pseudomonal infection with KDIGO recommended effluent rate of 25-35 mL/kg/h. The MIC values of each setting were an important factor to design piperacillin-tazobactam dosing regimens.