Fellowship
Cytopathology
Baylor Scott & White Medical Center, Temple, TX
2007
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Faculty
Faculty
Babak Shokrani, MD, FCAP
Associate Professor and Interim Chair
Department/Office
- Pathology
School/College
- College of Medicine
Education & Expertise
Education
Fellowship
Surgical Pathology
Barnes-Jewish Hospital, Washington University Medical Center, St Louis, MO
2006
Residency
Anatomic and Clinical Pathology
Howard University Hospital
2005
Doctor of Medicine (M.D.)
Medicine
Mashhad University of Medical Sciences
1995
Expertise
Surgical Pathology and Cytopathology
Academics
Academics
Organ System Unit 5 (OS-5), Sophomore Year Medical School, Howard University College of Medicine
Coordinator, Organ System Unit 5, Howard University College of Medicine
Pathology Small Group, Sophomore Year Medical School, Howard University College of Medicine
Research
Research
Funding
1R21CA199171-01A1 | FARUQUE (PI) | 04/01/2016 –03/31/2020 | NCI/NIH | $361.268
Co-investigator, Genetic Signatures Underlying Prostate Cancer Metastasis in African Americans
U54RR022762 | Blake (PI) | 9/1/ 2009-7/31/2010 | RTRN/NIH | $50,000
Co-investigator, Ultrastructural, Immunohistochemical and Biochemical Analysis of Small Leiomyomas
Ongoing Research Projects:
Principal Investigator: IRB-2023-1016: “Mucinous Adenocarcinoma of the head and neck, a review of the Literature and case series analysis in the African American Population.”
Principal Investigator: IRB-2023-0947: “Granular Cell Tumor a review of the Literature and case series analysis in the African American Population.”
IRB-12-MED-72: “A Collaborative Study Using Primary Prostate Cells and Their Reprogramming for the Study of Progression to Castrate Resistant Prostate Cancer”. Principal Investigator: Hudson, Tamaro, Ph.D.
IRB-2021-0187: “A concordance study between next generation sequencing (NGS) methods and conventional fluorescence in situ hybridization (FISH) for analyzing HER2 over-expression in malignant blood disorders and solid tumors”. Principal Investigator: Ali, Ahmed.
21-MED-13: “Evaluation of Immune Profiles In Autoimmune Diseases Using Archived Human Skin Biopsy Specimens.”
Accomplishments
Accomplishments
Annual Faculty Award in Teaching, Department of Pathology (2022)
Annual Faculty Award in Teaching, Department of Pathology (2021)
Attending Physician Leadership Award, Howard University Hospital Medical Staff (2020)
Honored Faculty Award, College of Medicine Honors and Oath Ceremony (2016)
Publications and Presentations
Publications and Presentations
Analysis of β-catenin Association with Obesity in African Americans with Premalignant and Malignant Colorectal Lesions
Background
African Americans (AA) are at high risk for Colorectal Cancer (CRC). Studies report a 30–60% increase in CRC risk with physical inactivity, obesity and metabolic syndrome. Activation of the WNT/β-catenin (CTNNB1) signaling pathway plays a critical role in colorectal carcinogenesis. Accumulating evidence also indicates a role of WNT-CTNNB1 signaling in obesity and metabolic diseases.
Aim
To examine the association between obesity, β-Catenin expression and colonic lesions in African Americans.
Diagnostic accuracy of a rapid diagnostic test for the early detection of COVID-19
Diagnostic accuracy of a rapid diagnostic test for the early detection of COVID-19
This study was undertaken to evaluate the diagnostic performance of the BinaxNOW COVID-19 Ag Card rapid antigen assay (Abbott; Chicago, IL, USA) in the detection of COVID-19 infection compared to the reference standard of PCR testing.
Metastatic Acral lentiginous melanoma
Metastatic Acral lentiginous melanoma: A case report and review
Of the four subtypes of cutaneous melanoma, acral lentiginous melanoma (ALM) is atypical in its presentation. ALM is a rare melanoma subtype that presents on the volar surfaces of the hand and foot. The difficulty of making an early diagnosis of ALM is highlighted by the case seen in our institution. The dire prognosis associated with ALM is postulated to be not only related to its destructive nature, but also due to a lack of patient awareness and vigilance, inadequate physician awareness, and disparity in healthcare access. We present this as a unique account of an ALM lesion in a 76 year old African-American male presenting originally in the left foot that went misdiagnosed for several years. The original lesion was considered to be an ulcerating left great toe lesion with signs typical of osteomyelitis. These clinical findings were corroborated by radiological x-ray evidence. Upon amputation and biopsy for suspected worsening osteomyelitis five years later, the pathological diagnosis of melanoma was finally made.
Factors influencing treatment outcome in hepatitis C virus minority patients at an inner-city hospital
Chronic hepatitis C virus (HCV) infection disproportionately affects African-Americans (AAs) and is a major contributor to liver failure and mortality. Genetic factors may not be the only cause in outcome disparity. We retrospectively investigated whether genetic host factors, viral genotypes, and treatment compliance in AA patients impacted the efficacy and the sustained virological response (SVR) rate of the interferon (IFN)-based treatment regimen. The medical chart review included 76 African-American patients (age ranging from 26 to 76) with varying levels of hepatitis condition. Fifty-seven (75%) of them had a clinically verifiable HCV infection and were followed by a hepatologist for 2 years at Howard University Hospital in Washington, DC. Both comprehensive metabolic profile and complete blood count analyses were performed.
"Multiple Primary Malignant Neoplasms in African Americans: A Case Series and Literature Review"
Sidhom F, Jackson D, Ali A, Shokrani, B, et al. (January 25, 2022) Multiple Primary Malignant Neoplasms in African
Americans: A Case Series and Literature Review. Cureus 14(1): e21585. doi:10.7759/cureus.21585